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The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway

The tumour suppressor p53 is a transcription factor that has evolved the ability to integrate distinct environmental signals including DNA damage, virus infection, and cytokine signaling into a common biological outcome that maintains normal cellular control. Mutations in p53 switch the cellular tra...

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Detalles Bibliográficos
Autores principales: Maclaine, Nicola J., Hupp, Ted R.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806026/
https://www.ncbi.nlm.nih.gov/pubmed/20157532