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"Shping 2" different cellular localizations - a potential new player in aging processes

The functions of the ubiquitously expressed protein tyrosine phosphatase Shp-2 are dependent on its localization. Cytosolic Shp-2 is known to modulate different pathways involved in cell growth, cell development, tissue inflammation and cellular chemotaxis. But Shp-2 is also localized in the nucleus...

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Detalles Bibliográficos
Autores principales: Jakob, Sascha, Altschmied, Joachim, Haendeler, Judith
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806037/
https://www.ncbi.nlm.nih.gov/pubmed/20157547