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Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors
BACKGROUND: Many neuromuscular blockers act as negative allosteric modulators of muscarinic acetylcholine receptors by decreasing affinity and potency of acetylcholine. The neuromuscular blocker rapacuronium has been shown to have facilitatory effects at muscarinic receptors leading to bronchospasm....
Autores principales: | Jakubík, Jan, Randáková, Alena, El-Fakahany, Esam E, Doležal, Vladimír |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806265/ https://www.ncbi.nlm.nih.gov/pubmed/20038295 http://dx.doi.org/10.1186/1471-2210-9-15 |
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