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p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program

The mitogen-activated protein kinase p38-γ is highly expressed in skeletal muscle and is associated with the dystrophin glycoprotein complex; however, its function remains unclear. After induced damage, muscle in mice lacking p38-γ generated significantly fewer myofibers than wild-type muscle. Notab...

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Detalles Bibliográficos
Autores principales: Gillespie, Mark A., Le Grand, Fabien, Scimè, Anthony, Kuang, Shihuan, von Maltzahn, Julia, Seale, Vanessa, Cuenda, Ana, Ranish, Jeffrey A., Rudnicki, Michael A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806273/
https://www.ncbi.nlm.nih.gov/pubmed/20026657
http://dx.doi.org/10.1083/jcb.200907037