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p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program
The mitogen-activated protein kinase p38-γ is highly expressed in skeletal muscle and is associated with the dystrophin glycoprotein complex; however, its function remains unclear. After induced damage, muscle in mice lacking p38-γ generated significantly fewer myofibers than wild-type muscle. Notab...
Autores principales: | Gillespie, Mark A., Le Grand, Fabien, Scimè, Anthony, Kuang, Shihuan, von Maltzahn, Julia, Seale, Vanessa, Cuenda, Ana, Ranish, Jeffrey A., Rudnicki, Michael A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806273/ https://www.ncbi.nlm.nih.gov/pubmed/20026657 http://dx.doi.org/10.1083/jcb.200907037 |
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