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Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
Ataxia telangiectasia mutated (ATM) plays a critical role in the cellular response to DNA damage. In response to DNA double-strand breaks (DSBs), ATM is autophosphorylated at serine 1981. Although this autophosphorylation is widely considered a sign of ATM activation, it is still not clear if autoph...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806275/ https://www.ncbi.nlm.nih.gov/pubmed/20026654 http://dx.doi.org/10.1083/jcb.200906064 |