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The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella

In humans, seven evolutionarily conserved genes that cause the cilia-related disorder Bardet-Biedl syndrome (BBS) encode proteins that form a complex termed the BBSome. The function of the BBSome in the cilium is not well understood. We purified a BBSome-like complex from Chlamydomonas reinhardtii f...

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Detalles Bibliográficos
Autores principales: Lechtreck, Karl-Ferdinand, Johnson, Eric C., Sakai, Tsuyoshi, Cochran, Deborah, Ballif, Bryan A., Rush, John, Pazour, Gregory J., Ikebe, Mitsuo, Witman, George B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806276/
https://www.ncbi.nlm.nih.gov/pubmed/20038682
http://dx.doi.org/10.1083/jcb.200909183