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Opposite-polarity motors activate one another to trigger cargo transport in live cells

Intracellular transport is typically bidirectional, consisting of a series of back and forth movements. Kinesin-1 and cytoplasmic dynein require each other for bidirectional transport of intracellular cargo along microtubules; i.e., inhibition or depletion of kinesin-1 abolishes dynein-driven cargo...

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Detalles Bibliográficos
Autores principales: Ally, Shabeen, Larson, Adam G., Barlan, Kari, Rice, Sarah E., Gelfand, Vladimir I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806283/
https://www.ncbi.nlm.nih.gov/pubmed/20038680
http://dx.doi.org/10.1083/jcb.200908075