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Opposite-polarity motors activate one another to trigger cargo transport in live cells
Intracellular transport is typically bidirectional, consisting of a series of back and forth movements. Kinesin-1 and cytoplasmic dynein require each other for bidirectional transport of intracellular cargo along microtubules; i.e., inhibition or depletion of kinesin-1 abolishes dynein-driven cargo...
Autores principales: | Ally, Shabeen, Larson, Adam G., Barlan, Kari, Rice, Sarah E., Gelfand, Vladimir I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806283/ https://www.ncbi.nlm.nih.gov/pubmed/20038680 http://dx.doi.org/10.1083/jcb.200908075 |
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