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The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells
PURPOSE: Glioblastoma multiforme (GBM) is resistant to current cytotoxic therapies, in part because of enhanced DNA repair. Activation of the receptor tyrosine kinase c-Met has been shown to protect cancer cells from DNA damage. We hypothesized that inhibiting c-Met would decrease this protection an...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806296/ https://www.ncbi.nlm.nih.gov/pubmed/20028557 http://dx.doi.org/10.1186/1748-717X-4-69 |