Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway

BACKGROUND: Epithelial to Mesenchymal Transition (EMT) induced by Transforming Growth Factor-β (TGF-β) is an important cellular event in organogenesis, cancer, and organ fibrosis. The process to reverse EMT is not well established. Our purpose is to define signaling pathways and transcription factor...

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Detalles Bibliográficos
Autores principales: Das, Shreyas, Becker, Bryan N, Hoffmann, F Michael, Mertz, Janet E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806300/
https://www.ncbi.nlm.nih.gov/pubmed/20025777
http://dx.doi.org/10.1186/1471-2121-10-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806300/
https://www.ncbi.nlm.nih.gov/pubmed/20025777
http://dx.doi.org/10.1186/1471-2121-10-94

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