Cargando…

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway

BACKGROUND: Epithelial to Mesenchymal Transition (EMT) induced by Transforming Growth Factor-β (TGF-β) is an important cellular event in organogenesis, cancer, and organ fibrosis. The process to reverse EMT is not well established. Our purpose is to define signaling pathways and transcription factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Das, Shreyas, Becker, Bryan N, Hoffmann, F Michael, Mertz, Janet E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806300/ https://www.ncbi.nlm.nih.gov/pubmed/20025777 http://dx.doi.org/10.1186/1471-2121-10-94

Ejemplares similares

Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins
por: Das, Shreyasi, et al.
Publicado: (2012)

Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1
por: Carriere, Patrick P., et al.
Publicado: (2015)

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition
por: Dong, Tianxiu, et al.
Publicado: (2016)

Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription
por: Wan, Guoqing, et al.
Publicado: (2020)

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
por: Kim, Taewan, et al.
Publicado: (2011)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

The role of epithelial–mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel‐resistant prostate cancer
por: Hanrahan, Karen, et al.
Publicado: (2017)

Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer
por: Prislei, Silvia, et al.
Publicado: (2015)

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma
por: Liu, Jijun, et al.
Publicado: (2018)

Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression
por: Horny, Kai, et al.
Publicado: (2023)

TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model
por: Leshem, Orit, et al.
Publicado: (2011)

Helicobacter pylori Initiates a Mesenchymal Transition through ZEB1 in Gastric Epithelial Cells
por: Baud, Jessica, et al.
Publicado: (2013)

Effect of AKT inhibition on epithelial-mesenchymal transition and ZEB1-potentiated radiotherapy in nasopharyngeal carcinoma
por: CHEN, WEIGUO, et al.
Publicado: (2013)

FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition
por: Abshire, C F, et al.
Publicado: (2016)

LDH-Apromotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer
por: Zhang, Yongjie, et al.
Publicado: (2018)

RAE1 mediated ZEB1 expression promotes epithelial–mesenchymal transition in breast cancer
por: Oh, Ji Hoon, et al.
Publicado: (2019)

Polydatin inhibits ZEB1‐invoked epithelial‐mesenchymal transition in fructose‐induced liver fibrosis
por: Zhao, Xiaojuan, et al.
Publicado: (2020)

Prognostic Role of Epithelial-Mesenchymal Transition Markers “E-Cadherin, β-Catenin, ZEB1, ZEB2 and p63” in Bladder Carcinoma
por: Moussa, Rabab Ahmed, et al.
Publicado: (2019)

The role of RhoC in epithelial-to-mesenchymal transition of ovarian carcinoma cells
por: Gou, Wen-feng, et al.
Publicado: (2014)

Overexpression of ZEB2‐AS1 promotes epithelial‐to‐mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma
por: Diao, Pengfei, et al.
Publicado: (2019)

HOXD9 promotes epithelial–mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma
por: Lv, Xiupeng, et al.
Publicado: (2015)

ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells
por: Guo, Cao, et al.
Publicado: (2017)

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition
por: Singh, Shalini, et al.
Publicado: (2016)

PARK2 negatively regulates the metastasis and epithelial-mesenchymal transition of glioblastoma cells via ZEB1
por: Wang, Haiyang, et al.
Publicado: (2017)

MTA1, a Target of Resveratrol, Promotes Epithelial-Mesenchymal Transition of Endometriosis via ZEB2
por: Kong, Xiangyi, et al.
Publicado: (2020)

PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1
por: Llorens, María Candelaria, et al.
Publicado: (2019)

Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1
por: Omar, Fatma A., et al.
Publicado: (2023)

Long non-coding RNA ZEB1-AS1 promotes cell invasion and epithelial to mesenchymal transition through inducing ZEB1 expression in cervical cancer
por: Cheng, Rongjie, et al.
Publicado: (2018)

miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1
por: Gao, Hai-Xiang, et al.
Publicado: (2016)

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis
por: Zhang, Nan, et al.
Publicado: (2017)

Knockdown of BAG3 induces epithelial–mesenchymal transition in thyroid cancer cells through ZEB1 activation
por: Meng, X, et al.
Publicado: (2014)

A case of pulmonary pleomorphic carcinoma with malignant phenotypes induced by ZEB1-associated epithelial-mesenchymal transition
por: Kondo, Mayo, et al.
Publicado: (2018)

Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium
por: Sun, Jian, et al.
Publicado: (2018)

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells
por: Pan, Bo, et al.
Publicado: (2018)

AB052. ZEB1 promotes vasculogenic mimicry formation in prostate cancer is associated with epithelial-mesenchymal transition
por: Wang, Hua, et al.
Publicado: (2017)

Nuclear factor I/B mediates epithelial-mesenchymal transition in human melanoma cells through ZEB1
por: Cheng, Ruimin, et al.
Publicado: (2021)

Long non‐coding RNA ZEB2‐AS1 promotes the proliferation, metastasis and epithelial mesenchymal transition in triple‐negative breast cancer by epigenetically activating ZEB2
por: Zhang, Guoxin, et al.
Publicado: (2019)

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
por: Sun, Zhenqiang, et al.
Publicado: (2021)

Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells
por: Handa, Haruka, et al.
Publicado: (2017)

The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2
por: Lee, Kwok Kin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gqh0gp60tc3ki1ca39mccfjm48