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Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway

BACKGROUND: Lewis y antigen is difucosylated oligosaccharide and is carried by glycoconjugates at cell surface. Elevated expression of Lewis y has been found in 75% of ovarian tumor, and the high expression level is correlated to the tumor's pathological staging and prognosis. This study was to...

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Detalles Bibliográficos
Autores principales: Liu, Juanjuan, Lin, Bei, Hao, Yingying, Qi, Yue, Zhu, Liancheng, Li, Feifei, Liu, Dawo, Cong, Jianping, Zhang, Shulan, Iwamori, Masao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806302/
https://www.ncbi.nlm.nih.gov/pubmed/20003467
http://dx.doi.org/10.1186/1756-9966-28-154