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Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase

Posttranslational histone modifications regulate both gene expression and genome integrity. Despite the dynamic nature of these modifications, appropriate real-time monitoring systems are lacking. In this study, we developed a method to visualize histone modifications in living somatic cells and pre...

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Detalles Bibliográficos
Autores principales: Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Nozaki, Naohito, Kimura, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806314/
https://www.ncbi.nlm.nih.gov/pubmed/19995936
http://dx.doi.org/10.1083/jcb.200904137