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The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella

Cilia and flagella are highly conserved microtubule (MT)-based organelles with motile and sensory functions, and ciliary defects have been linked to several human diseases. The 9 + 2 structure of motile axonemes contains nine MT doublets interconnected by nexin links, which surround a central pair o...

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Detalles Bibliográficos
Autores principales: Heuser, Thomas, Raytchev, Milen, Krell, Jeremy, Porter, Mary E., Nicastro, Daniela
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806320/
https://www.ncbi.nlm.nih.gov/pubmed/20008568
http://dx.doi.org/10.1083/jcb.200908067