ZnT3 mRNA levels are reduced in Alzheimer's disease post-mortem brain

BACKGROUND: ZnT3 is a membrane Zn(2+ )transporter that is responsible for concentrating Zn(2+ )into neuronal presynaptic vesicles. Zn(2+ )homeostasis in the brain is relevant to Alzheimer's disease (AD) because Zn(2+ )released during neurotransmission may bind to Aβ peptides, accelerating the a...

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Detalles Bibliográficos
Autores principales: Beyer, Nancy, Coulson, David TR, Heggarty, Shirley, Ravid, Rivka, Irvine, G Brent, Hellemans, Jan, Johnston, Janet A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806356/
https://www.ncbi.nlm.nih.gov/pubmed/20030848
http://dx.doi.org/10.1186/1750-1326-4-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806356/
https://www.ncbi.nlm.nih.gov/pubmed/20030848
http://dx.doi.org/10.1186/1750-1326-4-53

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