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Flux regulation of cardiac ryanodine receptor channels
The cardiac type 2 ryanodine receptor (RYR2) is activated by Ca(2+)-induced Ca(2+) release (CICR). The inherent positive feedback of CICR is well controlled in cells, but the nature of this control is debated. Here, we explore how the Ca(2+) flux (lumen-to-cytosol) carried by an open RYR2 channel in...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806413/ https://www.ncbi.nlm.nih.gov/pubmed/20008518 http://dx.doi.org/10.1085/jgp.200910273 |