Cargando…

Flux regulation of cardiac ryanodine receptor channels

The cardiac type 2 ryanodine receptor (RYR2) is activated by Ca(2+)-induced Ca(2+) release (CICR). The inherent positive feedback of CICR is well controlled in cells, but the nature of this control is debated. Here, we explore how the Ca(2+) flux (lumen-to-cytosol) carried by an open RYR2 channel in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yiwei, Porta, Maura, Qin, Jia, Ramos, Jorge, Nani, Alma, Shannon, Thomas R., Fill, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806413/ https://www.ncbi.nlm.nih.gov/pubmed/20008518 http://dx.doi.org/10.1085/jgp.200910273

Ejemplares similares

Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions
por: Chen, Haiyan, et al.
Publicado: (2013)

Luminal Ca(2+) Regulation of Single Cardiac Ryanodine Receptors: Insights Provided by Calsequestrin and its Mutants
por: Qin, Jia, et al.
Publicado: (2008)

Modulation of Cardiac Ryanodine Receptor Channels by Alkaline Earth Cations
por: Diaz-Sylvester, Paula L., et al.
Publicado: (2011)

Approaching ryanodine receptor therapeutics from the calcin angle
por: Ramos-Franco, Josefina, et al.
Publicado: (2016)

Calcium Regulation of Single Ryanodine Receptor Channel Gating Analyzed Using HMM/MCMC Statistical Methods
por: Rosales, Rafael A., et al.
Publicado: (2004)

Unitary Ca(2+) Current through Cardiac Ryanodine Receptor Channels under Quasi-Physiological Ionic Conditions
por: Mejía-Alvarez, Rafael, et al.
Publicado: (1999)

Ryanodine Receptor Adaptation
por: Fill, M., et al.
Publicado: (2000)

Unitary Ca(2+) Current through Mammalian Cardiac and Amphibian Skeletal Muscle Ryanodine Receptor Channels under Near-physiological Ionic Conditions
por: Kettlun, Claudia, et al.
Publicado: (2003)

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca(2+) Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor
por: Søndergaard, Mads Toft, et al.
Publicado: (2017)

mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel
por: Huang, Tai-Qin, et al.
Publicado: (2015)

Surface charge potentiates conduction through the cardiac ryanodine receptor channel
Publicado: (1994)

Association of cardiac myosin-binding protein-C with the ryanodine receptor channel – putative retrograde regulation?
por: Stanczyk, Paulina J., et al.
Publicado: (2018)

Interactions of a Reversible Ryanoid (21-Amino-9α-Hydroxy-Ryanodine) with Single Sheep Cardiac Ryanodine Receptor Channels
por: Tanna, Bhavna, et al.
Publicado: (1998)

CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors
por: Camors, Emmanuel, et al.
Publicado: (2014)

Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum
Publicado: (1992)

The structural basis of ryanodine receptor ion channel function
por: Meissner, Gerhard
Publicado: (2017)

Ryanodine receptors
por: Capes, E Michelle, et al.
Publicado: (2011)

Ryanoid Modification of the Cardiac Muscle Ryanodine Receptor Channel Results in Relocation of the Tetraethylammonium Binding Site
por: Tanna, Bhavna, et al.
Publicado: (2001)

A model for ionic conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum
Publicado: (1992)

Methanethiosulfonate Derivatives Inhibit Current through the Ryanodine Receptor/Channel
por: Quinn, Kerry E., et al.
Publicado: (1997)

The N-Terminal Region of the Ryanodine Receptor Affects Channel Activation
por: Faltinova, Andrea, et al.
Publicado: (2017)

Deciphering ryanodine receptor array operation in cardiac myocytes
por: Xie, Wenjun, et al.
Publicado: (2010)

Ryanodine receptor-mediated arrhythmias and sudden cardiac death
por: Blayney, Lynda M., et al.
Publicado: (2009)

Ryanodine receptors are part of the myospryn complex in cardiac muscle
por: Benson, Matthew A., et al.
Publicado: (2017)

Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain
por: Handhle, Ahmed, et al.
Publicado: (2016)

Molecular Basis of Ca(2)+ Activation of the Mouse Cardiac Ca(2)+ Release Channel (Ryanodine Receptor)
por: Li, Pin, et al.
Publicado: (2001)

The Ca2+-release channel/ryanodine receptor is localized in junctional and corbular sarcoplasmic reticulum in cardiac muscle
Publicado: (1993)

A mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment
por: Mukherjee, Saptarshi, et al.
Publicado: (2012)

Extensive Ca(2+) leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca(2+) hypersensitivity
por: Uehara, Akira, et al.
Publicado: (2017)

Investigations of the Contribution of a Putative Glycine Hinge to Ryanodine Receptor Channel Gating
por: Euden, Joanne, et al.
Publicado: (2013)

Coupling of SK channels, L-type Ca(2+) channels, and ryanodine receptors in cardiomyocytes
por: Zhang, Xiao-Dong, et al.
Publicado: (2018)

The ryanodine receptor/junctional channel complex is regulated by growth factors in a myogenic cell line
Publicado: (1991)

Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators
por: Chi, Ximin, et al.
Publicado: (2019)

Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle
por: Bellinger, Andrew M., et al.
Publicado: (2009)

Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment
por: Baker, Mariah R., et al.
Publicado: (2015)

The Interplay of Rogue and Clustered Ryanodine Receptors Regulates Ca(2+) Waves in Cardiac Myocytes
por: Chen, Xudong, et al.
Publicado: (2018)

Regulation of cardiac ryanodine receptor function by the cyclic-GMP dependent protein kinase G
por: Gonano, Luis A., et al.
Publicado: (2022)

Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation
por: Okolo, Chidinma A, et al.
Publicado: (2023)

Rapid Activation of the Cardiac Ryanodine Receptor by Submillisecond Calcium Stimuli
por: Zahradníková, A., et al.
Publicado: (1999)

Functional Characterization of the Cardiac Ryanodine Receptor Pore-Forming Region
por: Euden, Joanne, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ot1a7c4qn3nlg7sjnspe4vt9tf