Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

Th2 cells drive protective immunity against most parasitic helminths, but few mechanisms have been demonstrated that facilitate pathogen clearance. We show that IL-4 and IL-13 protect against intestinal lumen-dwelling worms primarily by inducing intestinal epithelial cells (IECs) to differentiate in...

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Detalles Bibliográficos
Autores principales: Herbert, De'Broski R., Yang, Jun-Qi, Hogan, Simon P., Groschwitz, Kathryn, Khodoun, Marat, Munitz, Ariel, Orekov, Tatyana, Perkins, Charles, Wang, Quan, Brombacher, Frank, Urban, Joseph F., Rothenberg, Marc E., Finkelman, Fred D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806463/
https://www.ncbi.nlm.nih.gov/pubmed/19995957
http://dx.doi.org/10.1084/jem.20091268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806463/
https://www.ncbi.nlm.nih.gov/pubmed/19995957
http://dx.doi.org/10.1084/jem.20091268

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