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MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4(hi) monocytes in obesity

Adipose tissue macrophages (ATMs) play a critical role in obesity-induced inflammation and insulin resistance. Distinct subtypes of ATMs have been identified that differentially express macrophage galactose-type C-type lectin 1 (MGL1/CD301), a marker of alternatively activated macrophages. To evalua...

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Detalles Bibliográficos
Autores principales: Westcott, Daniel J., DelProposto, Jennifer B., Geletka, Lynn M., Wang, Tianyi, Singer, Kanakadurga, Saltiel, Alan R., Lumeng, Carey N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806469/
https://www.ncbi.nlm.nih.gov/pubmed/19995956
http://dx.doi.org/10.1084/jem.20091333