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MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4(hi) monocytes in obesity
Adipose tissue macrophages (ATMs) play a critical role in obesity-induced inflammation and insulin resistance. Distinct subtypes of ATMs have been identified that differentially express macrophage galactose-type C-type lectin 1 (MGL1/CD301), a marker of alternatively activated macrophages. To evalua...
Autores principales: | Westcott, Daniel J., DelProposto, Jennifer B., Geletka, Lynn M., Wang, Tianyi, Singer, Kanakadurga, Saltiel, Alan R., Lumeng, Carey N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806469/ https://www.ncbi.nlm.nih.gov/pubmed/19995956 http://dx.doi.org/10.1084/jem.20091333 |
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