Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase–dependent manner

Nitrite (NO(2)(−)), previously viewed as a physiologically inert metabolite and biomarker of the endogenous vasodilator NO, was recently identified as an important biological NO reservoir in vasculature and tissues, where it contributes to hypoxic signaling, vasodilation, and cytoprotection after is...

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Detalles Bibliográficos
Autores principales: Cauwels, Anje, Buys, Emmanuel S., Thoonen, Robrecht, Geary, Lisa, Delanghe, Joris, Shiva, Sruti, Brouckaert, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806477/
https://www.ncbi.nlm.nih.gov/pubmed/19934018
http://dx.doi.org/10.1084/jem.20091236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806477/
https://www.ncbi.nlm.nih.gov/pubmed/19934018
http://dx.doi.org/10.1084/jem.20091236

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