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New PI(4,5)P(2)- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering
Integrin-dependent adhesion sites consist of clustered integrins that transmit mechanical forces and provide signaling required for cell survival and morphogenesis. Despite their importance, the regulation of integrin clustering by the cytoplasmic adapter protein talin (Tal) and phosphatidylinositol...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806581/ https://www.ncbi.nlm.nih.gov/pubmed/19948488 http://dx.doi.org/10.1083/jcb.200908134 |