New PI(4,5)P(2)- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering

Integrin-dependent adhesion sites consist of clustered integrins that transmit mechanical forces and provide signaling required for cell survival and morphogenesis. Despite their importance, the regulation of integrin clustering by the cytoplasmic adapter protein talin (Tal) and phosphatidylinositol...

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Detalles Bibliográficos
Autores principales: Saltel, Frédéric, Mortier, Eva, Hytönen, Vesa P., Jacquier, Marie-Claude, Zimmermann, Pascale, Vogel, Viola, Liu, Wei, Wehrle-Haller, Bernhard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806581/
https://www.ncbi.nlm.nih.gov/pubmed/19948488
http://dx.doi.org/10.1083/jcb.200908134

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