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The glycosaminoglycan-binding domain of PRELP acts as a cell type–specific NF-κB inhibitor that impairs osteoclastogenesis

Proline/arginine-rich end leucine-rich repeat protein (PRELP) is a glycosaminoglycan (GAG)- and collagen-binding anchor protein highly expressed in cartilage, basement membranes, and developing bone. We observed that PRELP inhibited in vitro and in vivo mouse osteoclastogenesis through its GAG-bindi...

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Detalles Bibliográficos
Autores principales:	Rucci, Nadia, Rufo, Anna, Alamanou, Marina, Capulli, Mattia, Del Fattore, Andrea, Åhrman, Emma, Capece, Daria, Iansante, Valeria, Zazzeroni, Francesca, Alesse, Edoardo, Heinegård, Dick, Teti, Anna
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806584/ https://www.ncbi.nlm.nih.gov/pubmed/19951916 http://dx.doi.org/10.1083/jcb.200906014

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