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Separating the spindle, checkpoint, and timer functions of BubR1

BubR1 performs several roles during mitosis, affecting the spindle assembly checkpoint (SAC), mitotic timing, and spindle function, but the interdependence of these functions is unclear. We have analyzed in Drosophila melanogaster the mitotic phenotypes of kinase-dead (KD) BubR1 and BubR1 lacking th...

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Detalles Bibliográficos
Autores principales: Rahmani, Zohra, Gagou, Mary E., Lefebvre, Christophe, Emre, Doruk, Karess, Roger E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806589/
https://www.ncbi.nlm.nih.gov/pubmed/19951912
http://dx.doi.org/10.1083/jcb.200905026