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Expressing functional siRNAs in mammalian cells using convergent transcription

BACKGROUND: The use of small interfering RNAs (siRNAs) as genetic inhibitors of gene expression has been shown to be an effective way of studying gene function in mammalian cells. Recently, different DNA vectors for expression of small hairpin RNAs (shRNAs) or co-expression of sense and antisense RN...

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Detalles Bibliográficos
Autores principales: Tran, Nham, Cairns, Murray J, Dawes, Ian W, Arndt, Greg M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280659/
https://www.ncbi.nlm.nih.gov/pubmed/14604435
http://dx.doi.org/10.1186/1472-6750-3-21