Cargando…

Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells

Focal adhesion disassembly is regulated by microtubules (MTs) through an unknown mechanism that involves dynamin. To test whether endocytosis may be involved, we interfered with the function of clathrin or its adaptors autosomal recessive hypercholesteremia (ARH) and Dab2 (Disabled-2) and found that...

Descripción completa

Detalles Bibliográficos
Autores principales: Ezratty, Ellen J., Bertaux, Claire, Marcantonio, Eugene E., Gundersen, Gregg G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806590/
https://www.ncbi.nlm.nih.gov/pubmed/19951918
http://dx.doi.org/10.1083/jcb.200904054