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An over-expression system for characterizing Ppt1 function in Drosophila

BACKGROUND: The infantile onset form of Neuronal Ceroid Lipofuscinoses (INCL) is the earliest and most severe form of NCL, with neurological symptoms that reflect massive neurodegeneration in the CNS and retina. INCL is due to recessively inherited mutations at the CLN1 locus. This locus encodes the...

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Detalles Bibliográficos
Autores principales: Korey, Christopher A, MacDonald, Marcy E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280676/
https://www.ncbi.nlm.nih.gov/pubmed/14629778