The Expression Level of CB(1) and CB(2) Receptors Determines Their Efficacy at Inducing Apoptosis in Astrocytomas

BACKGROUND: Cannabinoids represent unique compounds for treating tumors, including astrocytomas. Whether CB(1) and CB(2) receptors mediate this therapeutic effect is unclear. PRINCIPAL FINDINGS: We generated astrocytoma subclones that express set levels of CB(1) and CB(2), and found that cannabinoid...

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Detalles Bibliográficos
Autores principales: Cudaback, Eiron, Marrs, William, Moeller, Thomas, Stella, Nephi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806825/
https://www.ncbi.nlm.nih.gov/pubmed/20090845
http://dx.doi.org/10.1371/journal.pone.0008702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806825/
https://www.ncbi.nlm.nih.gov/pubmed/20090845
http://dx.doi.org/10.1371/journal.pone.0008702

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