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A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase

BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...

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Detalles Bibliográficos
Autores principales: Amano, Mutsuki, Tsumura, Yuta, Taki, Kentaro, Harada, Hidenori, Mori, Kazutaka, Nishioka, Tomoki, Kato, Katsuhiro, Suzuki, Takeshi, Nishioka, Yosuke, Iwamatsu, Akihiro, Kaibuchi, Kozo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806833/
https://www.ncbi.nlm.nih.gov/pubmed/20090853
http://dx.doi.org/10.1371/journal.pone.0008704