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A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase
BACKGROUND: Protein kinases are major components of signal transduction pathways in multiple cellular processes. Kinases directly interact with and phosphorylate downstream substrates, thus modulating their functions. Despite the importance of identifying substrates in order to more fully understand...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806833/ https://www.ncbi.nlm.nih.gov/pubmed/20090853 http://dx.doi.org/10.1371/journal.pone.0008704 |