Therapeutic Efficacy of Cintredekin Besudotox (IL13-PE38QQR) in Murine Lung Fibrosis Is Unaffected by Immunity to Pseudomonas aeruginosa Exotoxin A

BACKGROUND: We have previously explored a therapeutic strategy for specifically targeting the profibrotic activity of IL-13 during experimental pulmonary fibrosis using a fusion protein comprised of human IL-13 and a mutated form of Pseudomonas aeruginosa exotoxin A (IL13-PE) and observed that the i...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosada, Rogério S., Moreira, Ana P., Frantz, Fabiani G., Puri, Raj K., Rahman, Aquilur, Standiford, Theodore J., Zárate-Bladés, Carlos R., Silva, Célio L., Hogaboam, Cory M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806906/
https://www.ncbi.nlm.nih.gov/pubmed/20090941
http://dx.doi.org/10.1371/journal.pone.0008721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806906/
https://www.ncbi.nlm.nih.gov/pubmed/20090941
http://dx.doi.org/10.1371/journal.pone.0008721

Ejemplares similares