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The Liver-Selective Thyromimetic T-0681 Influences Reverse Cholesterol Transport and Atherosclerosis Development in Mice

BACKGROUND: Liver-selective thyromimetics have been reported to efficiently reduce plasma cholesterol through the hepatic induction of both, the low-density lipoprotein receptor (LDLr) and the high-density lipoprotein (HDL) receptor; the scavenger receptor class B type I (SR-BI). Here, we investigat...

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Detalles Bibliográficos
Autores principales: Tancevski, Ivan, Demetz, Egon, Eller, Philipp, Duwensee, Kristina, Hoefer, Julia, Heim, Christiane, Stanzl, Ursula, Wehinger, Andreas, Auer, Kristina, Karer, Regina, Huber, Julia, Schgoer, Wilfried, Van Eck, Miranda, Vanhoutte, Jonathan, Fievet, Catherine, Stellaard, Frans, Rudling, Mats, Patsch, Josef R., Ritsch, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806908/
https://www.ncbi.nlm.nih.gov/pubmed/20090943
http://dx.doi.org/10.1371/journal.pone.0008722