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Bordetella pertussis Commits Human Dendritic Cells to Promote a Th1/Th17 Response through the Activity of Adenylate Cyclase Toxin and MAPK-Pathways

The complex pathology of B. pertussis infection is due to multiple virulence factors having disparate effects on different cell types. We focused our investigation on the ability of B. pertussis to modulate host immunity, in particular on the role played by adenylate cyclase toxin (CyaA), an importa...

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Detalles Bibliográficos
Autores principales: Fedele, Giorgio, Spensieri, Fabiana, Palazzo, Raffaella, Nasso, Maria, Cheung, Gordon Yiu Chong, Coote, John Graham, Ausiello, Clara Maria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806909/
https://www.ncbi.nlm.nih.gov/pubmed/20090944
http://dx.doi.org/10.1371/journal.pone.0008734