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Bordetella pertussis Commits Human Dendritic Cells to Promote a Th1/Th17 Response through the Activity of Adenylate Cyclase Toxin and MAPK-Pathways
The complex pathology of B. pertussis infection is due to multiple virulence factors having disparate effects on different cell types. We focused our investigation on the ability of B. pertussis to modulate host immunity, in particular on the role played by adenylate cyclase toxin (CyaA), an importa...
Autores principales: | Fedele, Giorgio, Spensieri, Fabiana, Palazzo, Raffaella, Nasso, Maria, Cheung, Gordon Yiu Chong, Coote, John Graham, Ausiello, Clara Maria |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806909/ https://www.ncbi.nlm.nih.gov/pubmed/20090944 http://dx.doi.org/10.1371/journal.pone.0008734 |
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