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Influenza H5N1 and H1N1 Virus Replication and Innate Immune Responses in Bronchial Epithelial Cells Are Influenced by the State of Differentiation

Influenza H5N1 virus continues to be enzootic in poultry and transmits zoonotically to humans. Although a swine-origin H1N1 virus has emerged to become pandemic, its virulence for humans remains modest in comparison to that seen in zoonotic H5N1 disease. As human respiratory epithelium is the primar...

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Detalles Bibliográficos
Autores principales: Chan, Renee W. Y., Yuen, Kit M., Yu, Wendy C. L., Ho, Carol C. C., Nicholls, John M., Peiris, J. S. Malik, Chan, Michael C. W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806912/
https://www.ncbi.nlm.nih.gov/pubmed/20090947
http://dx.doi.org/10.1371/journal.pone.0008713