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Enhanced Binding of Poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 Promoter via an Extended Cytosine-Adenosine Repeat

BACKGROUND: We have identified a cytosine-adenosine (CA) repeat length polymorphism in the 5′-regulatory region of the human integrin α2 gene ITGA2 that begins at −605. Our objective was to establish the contribution of this polymorphism to the regulation of integrin α2β1 expression, which is known...

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Detalles Bibliográficos
Autores principales: Cheli, Yann, Williams, Shirley A., Ballotti, Robert, Nugent, Diane J., Kunicki, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806922/
https://www.ncbi.nlm.nih.gov/pubmed/20090957
http://dx.doi.org/10.1371/journal.pone.0008743