TYROSINE PHOSPHORYLATION OF COFILIN AT Y68 BY V-SRC LEADS TO ITS DEGRADATION THROUGH UBIQUITIN-PROTEASOME PATHWAY

Cofilin is a major regulator of actin dynamics involved in the regulation of cell spreading and migration through its actin depolymerizing and severing activities. V-Src is an activated Src tyrosine kinase and a potent oncogene known to phosphorylate a variety of cellular proteins in cell transforma...

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Detalles Bibliográficos
Autores principales: Yoo, Youngdong, Ho, Huei Jin, Wang, Chenran, Guan, Jun-Lin
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806939/
https://www.ncbi.nlm.nih.gov/pubmed/19802004
http://dx.doi.org/10.1038/onc.2009.319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806939/
https://www.ncbi.nlm.nih.gov/pubmed/19802004
http://dx.doi.org/10.1038/onc.2009.319

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