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TYROSINE PHOSPHORYLATION OF COFILIN AT Y68 BY V-SRC LEADS TO ITS DEGRADATION THROUGH UBIQUITIN-PROTEASOME PATHWAY
Cofilin is a major regulator of actin dynamics involved in the regulation of cell spreading and migration through its actin depolymerizing and severing activities. V-Src is an activated Src tyrosine kinase and a potent oncogene known to phosphorylate a variety of cellular proteins in cell transforma...
Autores principales: | Yoo, Youngdong, Ho, Huei Jin, Wang, Chenran, Guan, Jun-Lin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806939/ https://www.ncbi.nlm.nih.gov/pubmed/19802004 http://dx.doi.org/10.1038/onc.2009.319 |
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