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Dissection of the DNA Mimicry of the Bacteriophage T7 Ocr Protein using Chemical Modification

The homodimeric Ocr (overcome classical restriction) protein of bacteriophage T7 is a molecular mimic of double-stranded DNA and a highly effective competitive inhibitor of the bacterial type I restriction/modification system. The surface of Ocr is replete with acidic residues that mimic the phospha...

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Detalles Bibliográficos
Autores principales: Stephanou, Augoustinos S., Roberts, Gareth A., Cooper, Laurie P., Clarke, David J., Thomson, Andrew R., MacKay, C. Logan, Nutley, Margaret, Cooper, Alan, Dryden, David T.F.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806950/
https://www.ncbi.nlm.nih.gov/pubmed/19523474
http://dx.doi.org/10.1016/j.jmb.2009.06.020