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Rep Provides a Second Motor at the Replisome to Promote Duplication of Protein-Bound DNA

Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace the blocking protein-DNA complex. We show that Rep and UvrD...

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Detalles Bibliográficos
Autores principales: Guy, Colin P., Atkinson, John, Gupta, Milind K., Mahdi, Akeel A., Gwynn, Emma J., Rudolph, Christian J., Moon, Peter B., van Knippenberg, Ingeborg C., Cadman, Chris J., Dillingham, Mark S., Lloyd, Robert G., McGlynn, Peter
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807033/
https://www.ncbi.nlm.nih.gov/pubmed/19941825
http://dx.doi.org/10.1016/j.molcel.2009.11.009