Cargando…

An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

Interleukin-6 (IL-6) is an important modulator of inflammation and immunity whose dysregulation is associated with a number of disease states. There is evidence of significant heritability in inter-individual variation in IL6 gene expression but the genetic variants responsible for this remain to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Fairfax, Benjamin P., Vannberg, Fredrik O., Radhakrishnan, Jayachandran, Hakonarson, Hakon, Keating, Brendan J., Hill, Adrian V.S., Knight, Julian C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807371/
https://www.ncbi.nlm.nih.gov/pubmed/19942621
http://dx.doi.org/10.1093/hmg/ddp530