Molecular mechanism of regulation of OGG1: tuberin deficiency results in cytoplasmic redistribution of transcriptional factor NF-YA

The tuberous sclerosis complex (TSC) is caused by defects in one of two tumor suppressor genes, TSC-1 or TSC-2. TSC-2 gene encodes tuberin, a protein involved in the pathogenesis of kidney tumors, both angiomyolipomas and renal cell carcinomas. On the other hand, mice-deficient in the DNA repair enz...

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Detalles Bibliográficos
Autor principal: Habib, Samy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807420/
https://www.ncbi.nlm.nih.gov/pubmed/20040097
http://dx.doi.org/10.1186/1750-2187-4-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807420/
https://www.ncbi.nlm.nih.gov/pubmed/20040097
http://dx.doi.org/10.1186/1750-2187-4-8

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