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CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation

BACKGROUND: CXCR4, the receptor for the chemokine stromal-derived factor 1 (SDF-1), has been shown to mediate many of the processes essential for cancer progression such as tumor cell proliferation, metastasis, and angiogenesis. To understand the role of CXCR4 in the biology of neuroblastoma, a dise...

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Detalles Bibliográficos
Autores principales: Carlisle, Alex J, Lyttle, Christopher A, Carlisle, Rosalind Y, Maris, John M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807429/
https://www.ncbi.nlm.nih.gov/pubmed/20028517
http://dx.doi.org/10.1186/1476-4598-8-126