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Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics

BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regulation of cellular growth and development. While highly studied, it is still not fully understood how the signal is orchestrated. One of the reasons for the complexity of this pathway is the extensive n...

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Detalles Bibliográficos
Autores principales: Wang, Dennis YQ, Cardelli, Luca, Phillips, Andrew, Piterman, Nir, Fisher, Jasmin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807436/
https://www.ncbi.nlm.nih.gov/pubmed/20028552
http://dx.doi.org/10.1186/1752-0509-3-118