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Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics
BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regulation of cellular growth and development. While highly studied, it is still not fully understood how the signal is orchestrated. One of the reasons for the complexity of this pathway is the extensive n...
Autores principales: | Wang, Dennis YQ, Cardelli, Luca, Phillips, Andrew, Piterman, Nir, Fisher, Jasmin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807436/ https://www.ncbi.nlm.nih.gov/pubmed/20028552 http://dx.doi.org/10.1186/1752-0509-3-118 |
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