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The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness

BACKGROUND: rRNA adenine dimethyltransferases, represented by the Escherichia coli KsgA protein, are highly conserved phylogenetically and are generally not essential for growth. They are responsible for the post-transcriptional transfer of two methyl groups to two universally conserved adenosines l...

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Detalles Bibliográficos
Autores principales: Binet, Rachel, Maurelli, Anthony T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807437/
https://www.ncbi.nlm.nih.gov/pubmed/20043826
http://dx.doi.org/10.1186/1471-2180-9-279