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Conservation and Diversity of Influenza A H1N1 HLA-Restricted T Cell Epitope Candidates for Epitope-Based Vaccines

BACKGROUND: The immune-related evolution of influenza viruses is exceedingly complex and current vaccines against influenza must be reformulated for each influenza season because of the high degree of antigenic drift among circulating influenza strains. Delay in vaccine production is a serious probl...

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Detalles Bibliográficos
Autores principales: Tan, Paul ThiamJoo, Heiny, A. T., Miotto, Olivo, Salmon, Jerome, Marques, Ernesto T. A., Lemonnier, Francois, August, J. Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807450/
https://www.ncbi.nlm.nih.gov/pubmed/20090904
http://dx.doi.org/10.1371/journal.pone.0008754