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Manipulating IL-2 Availability Amid Presentation of Donor MHC Antigens Suppresses Murine Alloimmune Responses by Inducing Regulatory T Cells

BACKGROUND: Major histocompatibility complex (MHC) antigens are important for alloimmune responses as well as immune tolerance. Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon transplantation promotes transplant tolerance induced by...

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Detalles Bibliográficos
Autores principales: Zhang, Shuzi, Dai, Hehua, Wan, Ni, Moore, Yolonda, Dai, Zhenhua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807454/
https://www.ncbi.nlm.nih.gov/pubmed/20090908
http://dx.doi.org/10.1371/journal.pone.0008756